Resources · Briefs · Tools · Data

The resources we wish existed when we started.

Whitepapers, calculators, briefs, and reference data for the work of oncology adverse event grading. Free, practical, no contract required. Some are available today. More ship this quarter.

Subscribe to new release notifications Book a 30-minute conversation

Built for the people who grade adverse events for a living. CancerX member, HHS Cancer Moonshot Initiative. Two patents filed on the engine architecture.

01 / Available now

Three resources live today.

Each takes under five minutes to download or use. None require a contract or a sales call. Free, practical, the work itself.

Editorial cover for the 12-Pillar Implementation Playbook

PDF24 pages

For research directors, IT and procurement, sponsor clinical operations, CROs

The 12-Pillar Implementation Playbook

Future-state workflow maps. LMS-compatible training modules for coordinators, MDs, PIs, and monitors. Communication templates for medical executive committees, IRBs, sponsor monitors, and DSMBs. Drawn from Chirag Lodhia's real oncology deployments at Monash Health.

Most healthcare AI deployments hand the customer a license and walk away. This playbook is the work that ships with every Burna pilot.

Download the Playbook →

Editorial cover for the Query Economics Whitepaper

PDF8 pages

For CRO COOs, sponsor PV leadership, cancer center operations

The Query Economics of Oncology Trials

Three peer-reviewed sources synthesized (Pronker 2011, Tolmie 2011, Oracle ClearTrial 2021). Three portfolio scenarios with consistent math at conservative, typical, and stretch anchors. The architectural close that citation-bound grading provides.

Every oncology CRO is losing money to confirmation queries that would not be opened if rationale shipped with the original grade.

Download the Whitepaper →

Editorial cover for the AE Labor Cost Calculator

Live toolNo email

For VPs of Clinical Research Ops, CRO COOs, finance leadership

AE Labor Cost Calculator

Input your institution's parameters (coordinators, trials, average AEs per trial, current grading time). Get an estimate of annual labor hours, labor cost, estimated variability rate, downstream rework cost, and the platform's potential savings.

“20-30% variability in CTCAE grading” is abstract until you run your own numbers. The calculator turns it into your institution’s specific dollar figure.

Open the Calculator →

02 / In development

Five resources this quarter.

In active development. Subscribe to release notifications and receive a single email when each ships. Validation readouts and conference timing are included in the same quarterly briefing.

Subscribe to release notifications →

Editorial cover for the CTCAE v6.0 Lookup Tool

Ships this quarterLive tool

04 · INTERACTIVE WEB TOOL

CTCAE v6.0 Lookup Tool

For coordinators, oncologists, anyone learning v6.0

A searchable index of all 837+ CTCAE v6.0 criteria. Type a symptom, get the full Grade 1 through Grade 5 criteria, the System Organ Class, ICD-10 codes, common confounders, and a “what changed from v5.0” flag. Shareable URLs per term.

837+ termsv5 to v6 deltaFilter by SOC

Editorial cover for the CTCAE v6.0 Migration Guide

Ships this quarterPDF series

05 · PDF SERIES + CONSOLIDATED BRIEF

CTCAE v6.0 Migration Guide

For research operations leaders managing the v6.0 transition

The complete migration guide. The 20 highest-impact changes for oncology coordinators. Lab-based AE changes (anemia, neutropenia, thrombocytopenia). Symptom-based changes (fatigue, nausea, neuropathy). Multi-drug attribution under v6.0. Practical retraining steps.

5 to 7 partsTop 20 changesRetraining steps

Ships this quarterOpen source

06 · GITHUB + NPM + PYTHON

Open-Source CTCAE v6.0 Dataset

For clinical informatics developers, EHR integration teams, healthcare AI builders

Full CTCAE v6.0 dataset (837+ terms) as structured JSON and CSV. v5.0 to v6.0 delta dataset. Programmatic access via packages. The criteria are NCI public; nobody has published them as a clean, machine-readable dataset.

@burna-ai/ctcaepip install ctcae

Editorial cover for the CTCAE Variability Calculator

In developmentLive tool

07 · INTERACTIVE WEB TOOL

CTCAE Variability Calculator

For clinical research directors, VP Clinical Operations, sponsor monitoring leadership

Estimate your institution's CTCAE grading variability based on coordinator count, training tenure mix, and trial complexity. Pair with the AE Labor Cost Calculator to estimate the downstream rework cost. Industry baseline of 20% to 30% variability (Hong, Hillman, Le-Rademacher) is the comparator.

Pairs with §1.03Hong, Hillman baselinesRework cost output

Editorial cover for the Grade My Note service

Ships this quarterManual response · 24h

08 · SUBMISSION FORM · 24-HOUR TURNAROUND

Grade My Note

For oncologists and coordinators who want to experience the engine on real data before a pilot conversation

Paste a de-identified clinical note. Optionally provide the regimen. Receive within 24 hours a formatted grading report with adverse events identified, CTCAE grades, source-text citations, and per-drug attribution probability scores. Free, no contract, no commitment. Most oncology AI vendors require a six-month pilot before you can run a single note through the engine. We do the opposite.

24h responseDe-identified onlyNo commitment

03 / Clinical Intelligence Weekly

The newsletter for the people grading the work.

One CTCAE v6.0 change in depth. One real (anonymized) clinical scenario and how it should be graded. One new resource when one ships. Free, every week.

Free · weekly · oncology

Written for the practitioners who grade the work.

Each issue covers one CTCAE v6.0 change in depth, walks through a real (anonymized) clinical scenario, and surfaces the resources that shipped that week. No marketing cadence, no tracking beacons.

Unsubscribe anytime. Read by oncology research operations across cancer centers, CROs, and pharma.

05 / The deeper library

For procurement, validation, and audience-specific reading.

For something the library does not yet contain, email hello@burna.ai with the resource you wish existed. We are building the library readers ask for.

A / Procurement and Architecture

Architecture and Implementation Brief5-page CISO brief · security@burna.ai
The Engine, in depth/engine
Protocol Safe technical brief8-page brief · partnerships@burna.ai
Protocol Safe overview/protocol-safe

B / Validation

Validation methodology and studies in flight/validation
Pre-print archive on medRxivUpdated within 60 days of database lock
Target venuesJCO · JAMIA · JCO CCI · Annals of Oncology
Bio-IT World 2026 poster1,200-chart retrospective accuracy

C / Pricing and Pilot

D / Patient-side and Postmarket

Care Journal/care-journal
Patients and families/patients
Postmarket pharmacovigilance/postmarket-pv
2027 design partner cohortScoping conversations open through 2026

06 / Final

Use what is live. Get the rest as it ships.

The Implementation Playbook, the Query Economics Whitepaper, and the AE Labor Cost Calculator are available today. Five more resources ship this quarter.

Get the next resource the day it ships

A single email per resource. Validation readouts, platform updates, and conference timing are included in the same quarterly briefing.

No tracking beacons, no marketing email cadence.

Subscribe to release notifications → →

Or talk to us

Book a 30-minute conversation

If you would rather walk through the platform directly, the 30-minute conversation with Nnenna covers the engine, the validation roadmap, and where Burna fits in your stack.

Book a 30-minute conversation → →

The resources we wish existed when we started.

Whitepapers, calculators, briefs, and reference data for the work of oncology adverse event grading. Free, practical, no contract required. Some are available today. More ship this quarter.

Built for the people who grade adverse events for a living. CancerX member, HHS Cancer Moonshot Initiative. Two patents filed on the engine architecture.